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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STON2 All Species: 11.21
Human Site: T248 Identified Species: 22.42
UniProt: Q8WXE9 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WXE9 NP_149095.2 905 101165 T248 S C P L P P V T S P L K P N T
Chimpanzee Pan troglodytes XP_001135210 905 101144 T248 S C P L P P V T S P L K P N T
Rhesus Macaque Macaca mulatta XP_001105584 896 100013 T248 S C P L A P I T S P L K P N T
Dog Lupus familis XP_864856 735 82747 L123 T S G G G S S L L P T K S T C
Cat Felis silvestris
Mouse Mus musculus Q8BZ60 895 99593 P248 P S P P V P S P K K P N T P S
Rat Rattus norvegicus NP_001129346 895 99472 P248 P S P T V P S P K K P N A P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505629 865 95494 S248 S P P S T S P S K S D S P S R
Chicken Gallus gallus XP_421302 887 99388 T248 T D T S A L E T Q A P D V N F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001028915 859 96510 D247 N N S I F A F D N T L S K N S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24212 1262 137751 D277 P A A P E A D D L L D M F G T
Honey Bee Apis mellifera XP_396872 1188 129859 G418 S D L L G D F G E P I T T D T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795059 1041 114812 E302 L E V S R F S E V A T G P E T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 96.9 31.4 N.A. 86.1 85.8 N.A. 68 69.8 N.A. 48.5 N.A. 23.6 24.7 N.A. 25.5
Protein Similarity: 100 99.6 98 49.5 N.A. 90 89.7 N.A. 76.8 79.8 N.A. 61.7 N.A. 38.7 40 N.A. 44.6
P-Site Identity: 100 100 86.6 13.3 N.A. 13.3 13.3 N.A. 20 13.3 N.A. 13.3 N.A. 6.6 26.6 N.A. 13.3
P-Site Similarity: 100 100 93.3 20 N.A. 20 20 N.A. 33.3 20 N.A. 40 N.A. 6.6 40 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 9 0 17 17 0 0 0 17 0 0 9 0 0 % A
% Cys: 0 25 0 0 0 0 0 0 0 0 0 0 0 0 9 % C
% Asp: 0 17 0 0 0 9 9 17 0 0 17 9 0 9 0 % D
% Glu: 0 9 0 0 9 0 9 9 9 0 0 0 0 9 0 % E
% Phe: 0 0 0 0 9 9 17 0 0 0 0 0 9 0 9 % F
% Gly: 0 0 9 9 17 0 0 9 0 0 0 9 0 9 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 9 0 0 9 0 0 0 9 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 25 17 0 34 9 0 0 % K
% Leu: 9 0 9 34 0 9 0 9 17 9 34 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % M
% Asn: 9 9 0 0 0 0 0 0 9 0 0 17 0 42 0 % N
% Pro: 25 9 50 17 17 42 9 17 0 42 25 0 42 17 0 % P
% Gln: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 9 % R
% Ser: 42 25 9 25 0 17 34 9 25 9 0 17 9 9 25 % S
% Thr: 17 0 9 9 9 0 0 34 0 9 17 9 17 9 50 % T
% Val: 0 0 9 0 17 0 17 0 9 0 0 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _